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p-AKT2 (S474) Peptide

p-AKT2 (S474) Peptide

Cat no: BS4720P


Supplier: Bioworld Technology, Inc.
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AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.
Catalogue number: BS4720P
Applications: Block/Neutralize/Inhibit
Swiss prot: P31751
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-AKT2 (S474). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta; AKT2; PKBbeta;
Additional info: This peptide can be used with studies using BS4720 p-AKT2 (S474) pAb.

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