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p-APC (S2054) Peptide

p-APC (S2054) Peptide

Cat no: BS4649P

Supplier: Bioworld Technology, Inc.
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Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates beta-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Catalogue number: BS4649P
Applications: Block/Neutralize/Inhibit
Swiss prot: P25054
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-APC (S2054). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5; APC; DP2.5
Additional info: This peptide can be used with studies using BS4649 p-APC (S2054) pAb.

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