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p-AR-(beta)2 (S346) pAb

p-AR-(beta)2 (S346) pAb

Cat no: BS4652

Supplier: Bioworld Technology, Inc.
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Beta 2 Adrenergic Receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.
Catalogue number: BS4652
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P07550
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human AR-(beta)2 around the phosphorylation site of Serine 346.
Species: p-AR-(beta)2 (S346) pAb detects endogenous levels of AR-(beta)2 protein only when phosphorylated at Ser346.
Molecular weight: ~ 47 kDa, 68 kDa (glycosylated), 95 kDa (Dimer)
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: ADRB2; ADRB2R; ADRBR; B2AR; BAR; BETA2AR; Beta-2 adrenergic receptor; AR(beta)2
Additional info: For research use only, not for use in diagnostic procedure.

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