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p-Casein Kinase II(beta) (S209) pAb

p-Casein Kinase II(beta) (S209) pAb

Cat no: BS4660

Supplier: Bioworld Technology, Inc.
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Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI(alpha), (gamma), E and (delta), have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an (alpha)2(beta)2 or an (alpha)(alpha)'(beta)2 structure. The (alpha) catalytic subunit is stimulated by the (beta) regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Catalogue number: BS4660
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P67870
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human Casein Kinase II(beta) around the phosphorylation site of Serine 209.
Species: p-Casein Kinase II(beta) (S209) pAb detects endogenous levels of Casein Kinase II(beta) protein only when phosphorylated at Ser209.
Molecular weight: ~ 25 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a; CSNK2B; CK2N; G5A; CKII(beta); CK2B
Additional info: For research use only, not for use in diagnostic procedure.

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