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p-Caspase-6 (S257) Peptide

p-Caspase-6 (S257) Peptide

Cat no: BS4219P

Supplier: Bioworld Technology, Inc.
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Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. The cleavage of this protein causes cell membrane malfunction, membrane blebbing and eventual cell death.
Catalogue number: BS4219P
Applications: Block/Neutralize/Inhibit
Swiss prot: P55212
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Caspase-6 (S257). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Caspase-6; Caspase6; Caspase 6; CASP-6; poptotic protease Mch-2; Caspase-6 subunit p11; CASP6; MCH2
Additional info: This peptide can be used with studies using BS4219 p-Caspase-6 (S257) pAb.

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