p-Caspase-8 (Y380) Peptide

Cat no: BS4662P

Supplier: Bioworld Technology, Inc.

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Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.

Catalogue number:	BS4662P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q14790
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-Caspase-8 (Y380). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Caspase-8; Caspase8; Caspase 8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH; Caspase-8 subunit p18; Caspase-8 subunit p10; CASP8; MCH5
Additional info:	This peptide can be used with studies using BS4662 p-Caspase-8 (Y380) pAb.

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p-Caspase-8 (Y380) Peptide

Cat no: BS4662P

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