p-CaSR (T888) Peptide

Cat no: BS4663P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The calcium sensing receptor (CaSR) has been shown to play a major role in regulating parathyroid hormone secretion and subsequently influencing the calcium concentration of extracellular fluids. Based on sequence analysis of cDNA clones it appears that the CaSR is similar to the 7-transmembranedomain G-protein-coupled receptor superfamily. Changes in extracellular calcium are thought to modulate a balance between proliferation and differentiation in a variety of cell types. In normal primary keratinocytes and breast epithelial cells, proliferation is inhibited and elevated extracellular calcium levels trigger differentiation. Malignant transformations of these cell types are accompanied by a loss of responsiveness to the anti-proliferative effects of elevated extracellular calcium.

Catalogue number:	BS4663P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P41180
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-CaSR (T888). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Extracellular calcium-sensing receptor; CaSR; Parathyroid cell calcium-sensing receptor 1; PCaR1; CASR; GPRC2A; PCAR1
Additional info:	This peptide can be used with studies using BS4663 p-CaSR (T888) pAb.

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p-CaSR (T888) Peptide

Cat no: BS4663P

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