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p-Catenin-beta (S37) Peptide

p-Catenin-beta (S37) Peptide

Cat no: BS4739P

Supplier: Bioworld Technology, Inc.
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beta-Catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. CK1 phosphorylates beta-catenin at Ser45. This phosphorylation event primes beta-catenin for subsequent phosphorylation by GSK-3beta. GSK-3beta destabilizes beta-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of beta-catenin protein levels and have been found in many tumor cell lines.
Catalogue number: BS4739P
Applications: Block/Neutralize/Inhibit
Swiss prot: P35222
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Catenin-beta (S37). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Catenin beta; Cateninbeta; Catenin beta-1; Beta-catenin; CTNNB1; CTNNB; ORF Names: OK/SW-cl.35; PRO2286
Additional info: This peptide can be used with studies using BS4739 p-Catenin-beta (S37) pAb.

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