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p-CD31/PECAM1 (Y713) Peptide

p-CD31/PECAM1 (Y713) Peptide

Cat no: BS4666P

Supplier: Bioworld Technology, Inc.
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CD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells and endothelial cells, and modulates cell adhesion, endothelial cell migration and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical stress or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain containing binding partners such as PI3-kinase, SHIP, PLCgamma and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.
Catalogue number: BS4666P
Applications: Block/Neutralize/Inhibit
Swiss prot: P16284
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-CD31/PECAM1 (Y713). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD31; PECAM1
Additional info: This peptide can be used with studies using BS4666 p-CD31/PECAM1 (Y713) pAb.

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