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p-Cofilin 1 (S3) Peptide

p-Cofilin 1 (S3) Peptide

Cat no: BS5063P

Supplier: Bioworld Technology, Inc.
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Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly, essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous F-Actin by bridging two longitudinally-associated Actin subunits, changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser 3 by factors like opsonized zymosan. LIM kinase 1 (LIMK-1), a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerize F-Actin.
Catalogue number: BS5063P
Applications: Block/Neutralize/Inhibit
Swiss prot: P23528
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Cofilin 1 (S3). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform; CFL1; CFL
Additional info: This peptide can be used with studies using BS5063 p-Cofilin 1 (S3) pAb.

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