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p-Dab1 (Y232) Peptide

p-Dab1 (Y232) Peptide

Cat no: BS4643P

Supplier: Bioworld Technology, Inc.
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Dab1, a homolog of the Drosophila Disabled protein, is an adaptor protein involved in neural development. This cytoplasmic protein is tyrosine-phosphorylated during rapid expansion of the developing nervous system, and it is thought to interact with other proteins via a domain similar to the PTB domains of the Shc family. Dab1 has been shown to interact with the SH2 domains of Src, Fyn and Abl. Mutations in Dab1 result in widespread abnormalities in the brain, similar to those seen in Reelin mutants. Reelin is a secreted protein thought to play a role in directing migrating neurons. Evidence suggests that Dab1 functions downstream of Reelin in a signaling pathway involved in positioning cells in the developing brain
Catalogue number: BS4643P
Applications: Block/Neutralize/Inhibit
Swiss prot: O75553
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Dab1 (Y232). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Disabled homolog 1; DAB1
Additional info: This peptide can be used with studies using BS4643 p-Dab1 (Y232) pAb.

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