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p-Dok-2 (Y299) pAb

p-Dok-2 (Y299) pAb

Cat no: BS4786


Supplier: Bioworld Technology, Inc.
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Dok-1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Evidence suggests that p62 Dok-1 is a substrate of the constitutive tyrosine kinase activity of p210 Bcr-Abl, a fusion protein caused by the t(9;22) translocation and associated with chronic myelogenous leukemia. Dok-1, as well as the tyrosine kinase substrates IRS-1 and Cas, is a member of a class of
Catalogue number: BS4786
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: O60496
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human Dok-2 around the phosphorylation site of Tyrosine 299.
Species: p-Dok-2 (Y299) pAb detects endogenous levels of Dok-2 protein when phosphorylated at Tyr299.
Molecular weight: ~ 56 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2); DOK2
Additional info: For research use only, not for use in diagnostic procedure.

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