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p-ER(beta) (S105) pAb

p-ER(beta) (S105) pAb

Cat no: AP0318

Supplier: Bioworld Technology, Inc.
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Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERa and ERb, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERa and ERb have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes.
Catalogue number: AP0318
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q92731
Dilutions: WB:1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human ER(beta) around the phosphorylation site of Serine 105.
Species: p-ER(beta)(S105) pAb detects endogenous levels of ER(beta) protein only when phosphorylated at Ser105.
Molecular weight: ~ 48, 60 kDa
Purity: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: ER BETA; ER BETA; ER-beta; Erb; ESR 2; ESR 2; ESR B; ESR B; ESR BETA; ESR BETA; ESR2; ESR2; ESR2; ESRB; ESRB; ESTRB; Estrogen Receptor 2; Estrogen Receptor 2; Estrogen receptor beta; NR3A2; Nuclear receptor subfamily 3 group A member 2;
Additional info: For research use only, not for use in diagnostic procedure.

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