p-ERalpha (Y537) Peptide

Cat no: BS4683P

Supplier: Bioworld Technology, Inc.

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Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERalpha and ERbeta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus , though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERalpha and ERbeta have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERalpha and ERbeta may be regulated by distinct mechanisms even though they share many functional characteristics.

Catalogue number:	BS4683P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P03372
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-ERalpha (Y537). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Estrogen receptor; ER-alpha; ER; ESR1; ESR; NR3A1
Additional info:	This peptide can be used with studies using BS4683 p-ERalpha (Y537) pAb.

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p-ERalpha (Y537) Peptide

Cat no: BS4683P

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