p-Erbin (Y1104) pAb

Cat no: BS4826

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.

Catalogue number:	BS4826
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug/100ul
Swiss prot:	Q96RT1
Dilutions:	WB: 1:500~1:1000
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic phosphopeptide derived from human Erbin around the phosphorylation site of Tyrosine 1104.
Species:	p-Erbin (Y1104) pAb detects endogenous levels of Erbin protein only when phosphorylated at Tyr1104.
Molecular weight:	~ 172 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Protein LAP2; Densin-180-like protein; Erbb2-interacting protein; Erbin; ERBIN; KIAA1225; LAP2; ERBB2IP
Additional info:	For research use only, not for use in diagnostic procedure.

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p-Erbin (Y1104) pAb

Cat no: BS4826

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