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p-ERF (T526) Peptide

Cat no: BS4312P

p-ERF (T526) Peptide

ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.

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SPECIFICATIONS

Catalog Number

BS4312P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide p-ERF (T526). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P50548

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS4312 p-ERF (T526) pAb.

Alternative Names

ERF; ERF; ETS domain containing transcription factor ERF; ETS domain-containing transcription factor ERF; Ets2 repressor factor; PE 2; PE-2; PE2;

SUPPLIER INFO

Bioworld Technology, Inc.

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