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p-Gab1 (Y659) Peptide

p-Gab1 (Y659) Peptide

Cat no: BS5074P

Supplier: Bioworld Technology, Inc.
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Gab 1 (GRB2-associated binder 1), one such member of the IRS family, plays an important role in cellular growth response, transformation and apoptosis. Gab 1 is a multi-substrate docking protein that functions downstream in the signaling pathways of different receptor kinases, including EGFR. Gab1 is tyrosine phosphorylated normally in response to insulin and consequently enhances phosphatidylinositol 3- kinase (PI3K) binding. In response to osmotic shock, tyrosine-phosphorylated Gab 1 (p-Gab 1) also binds and activates phosphatidylinositol 3-kinase, suggesting that Gab 1 is the major site for PI3K recruitment following osmotic shock stimulation.
Catalogue number: BS5074P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q13480
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Gab1 (Y659). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1; GAB1
Additional info: This peptide can be used with studies using BS5074 p-Gab1 (Y659) pAb.

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