p-GATA1 (S142) Peptide

Cat no: BS5075P

Supplier: Bioworld Technology, Inc.

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Additional Information

GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.

Catalogue number:	BS5075P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P15976
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-GATA1 (S142). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein; GATA1; 2623; GATA1; 190685; P15976; ERYF1; GF1; NFE1;
Additional info:	This peptide can be used with studies using BS5075 p-GATA1 (S142) pAb.

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p-GATA1 (S142) Peptide

Cat no: BS5075P

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