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p-GluR-2 (S880) pAb

p-GluR-2 (S880) pAb

Cat no: BS4794

Supplier: Bioworld Technology, Inc.
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Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
Catalogue number: BS4794
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P42262
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human GluR2 around the phosphorylation site of Serine 880.
Species: p-GluR-2 (S880) pAb detects endogenous levels of GluR-2 protein only when phosphorylated at Ser880.
Molecular weight: ~ 100 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: AMPA 2; AMPA 2; AMPA selective glutamate receptor 2; AMPA-selective glutamate receptor 2; AMPA2; Glu R2; Glu RB; GluA2; GluR 2; GluR B; GluR B flop; GluR K2; GluR-2; GluR-B; GluR-K2; GLUR2; GluRB; Glutamate receptor 2; Glutamate receptor ionotropic AMPA 2; Glutamate receptor ionotropic AMPA2; Glutamate receptor ionotropic; Gria 2; Gria2; GRIA2; HBGR 2; HBGR2;
Additional info: For research use only, not for use in diagnostic procedure.

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