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p-IkB-(beta) (S23) pAb

p-IkB-(beta) (S23) pAb

Cat no: BS4106


Supplier: Bioworld Technology, Inc.
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The NF-kB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IkB proteins.The regulation of IkB(beta) and IkBE is similar to that of IkB(alpha). However, the phosphorylation and ubiquitin-mediated degradation of these proteins occurs with much slower kinetics. IKK phosphorylation of IkB(beta) occurs at Ser19 and Ser23, while IkBE can be phosphorylated at Ser18 and Ser22 . The human sequence of IkB-(beta) has also been reported to contain a threonine at position 19 suggesting that phosphorylation could be Thr19/Ser23.
Catalogue number: BS4106
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q15653
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human IkB-(beta) around the phosphorylation site of Serine 23.
Species: p-IkB-(beta) (S23) pAb detects endogenous levels of IkB-(beta) protein only when phosphorylated at Ser23.
Molecular weight: ~ 48 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: I kappa B beta; IKB B; IKB beta; IKBB; IkBbeta; IkappaBbeta; NF kappa B inhibitor beta; NF kappa BIB; NFKBIB; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor beta; TR interacting protein 9; TRIP 9; TRIP9; Thyroid receptor
Additional info: For research use only, not for use in diagnostic procedure.

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