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p-Insulin Receptor (Y1355) Peptide

Cat no: BS4270P

p-Insulin Receptor (Y1355) Peptide

The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.

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SPECIFICATIONS

Catalog Number

BS4270P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide p-Insulin Receptor (Y1355). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P06213

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS4270 p-Insulin Receptor (Y1355) pAb.

Alternative Names

CD 220; CD220; CD220 antigen; HHF 5; HHF5; human insulin receptor; INSR; INSR; Insulin receptor subunit beta; IR 1; IR; IR-1; IR1;

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