p-Kv1.3 (Y187) pAb

KCNA3 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

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SPECIFICATIONS

Catalog Number

BS4701

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic phosphopeptide derived from human Kv1.3 around the phosphorylation site of Tyrosine 187.

Species

p-Kv1.3 (Y187) pAb detects endogenous levels of human Kv1.3 protein only when phosphorylated at Tyr187. This antibody also detects endogenous levels of mouse and rat Kv3.1 protein when phosphorylated at the corresponding residues. This antibody also recognizes human HCG1642166 (isoform CRA_b) when phosphorylated at Tyr135.

Dilutions

WB: 1:500~1:1000

Swiss Prot

P22001

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 58 to 67 kDa

Alternative Names

Potassium voltage-gated channel subfamily A member 3; HGK5; HLK3; HPCN3; Voltage-gated K(+) channel HuKIII; Voltage-gated potassium channel subunit Kv1.3; KCNA3; HGK5; MK3