p-LIMK1/2 (T508/505) Peptide

Cat no: BS5025P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.

Catalogue number:	BS5025P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P53667/P53671
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-LIMK1/2 (T508/505). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	LIM domain kinase 1; LIMK-1; LIMK1; LIMK; LIM domain kinase 2; LIMK 2; LIMK2
Additional info:	This peptide can be used with studies using BS5025 p-LIMK1/2 (T508/505) pAb.

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p-LIMK1/2 (T508/505) Peptide

Cat no: BS5025P

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