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p-MEF-2 (T312) pAb

p-MEF-2 (T312) pAb

Cat no: BS4120

Supplier: Bioworld Technology, Inc.
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The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.
Catalogue number: BS4120
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug/100ul
Swiss prot: Q02078
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human MEF-2 around the phosphorylation site of Threonine 312.
Species: p-MEF-2 (T312) pAb detects endogenous levels of MEF-2 protein only when phosphorylated at Thr312
Molecular weight: ~ 55 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: MEF2 , MEF2A , MEF2A , Myocyte enhancer factor 2A , Myocyte-specific enhancer factor 2A , RSRFC4 , RSRFC9 ,
Additional info: For research use only, not for use in diagnostic procedure.

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