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p-MEK-3 (S189) pAb

p-MEK-3 (S189) pAb

Cat no: BS4123


Supplier: Bioworld Technology, Inc.
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The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinaseegulatory threonine and tyrosine residues present in thehr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6hosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.
Catalogue number: BS4123
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P46734
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human MEK-3 around the phosphorylation site of Serine 189.
Species: p-MEK-3 (S189) pAb detects endogenous levels of MEK-3 protein only when phosphorylated at Ser189
Molecular weight: ~ 39 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: MAP2K3; EC 2.7.12.2; MAPKK3; MEK3; MKK3; PRKMK3
Additional info: For research use only, not for use in diagnostic procedure.

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