p-NOS1 (S852) pAb

Cat no: BS4274

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.

Catalogue number:	BS4274
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P29475
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic phosphopeptide derived from human NOS1 around the phosphorylation site of Serine 852.
Species:	p-NOS1 (S852) pAb detects endogenous levels of NOS1 protein only when phosphorylated at Ser852
Molecular weight:	~ 43,125,149,160 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	NOS1; IHPS1; N-NOS; NC-NOS; NOS; Bnos; nNOS
Additional info:	For research use only, not for use in diagnostic procedure.

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p-NOS1 (S852) pAb

Cat no: BS4274

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