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p-PKC 0 (T538) Peptide

p-PKC 0 (T538) Peptide

Cat no: AP0292P

Supplier: Bioworld Technology, Inc.
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Members of the protein kinase C (PKC) family of serine/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types. PKC theta is a member of the PKC family, and its predominant expression in hematopoietic cells suggests that it may play a role in signal transduction and growth regulatory pathways unique to these cells. PKC theta is a Ca(2+)-independent PKC isoform that is selectively expressed in T lymphocytes (and muscle), and it is thought to play an important role in T cell receptor-induced activation. Among several PKC isoenzymes expressed in T cells, PKC theta is unique in being rapidly recruited to the site of TCR clustering. It has been shown that PKC theta is essential for TCR-mediated T-cell activation, but it is dispensable during TCR-dependent thymocyte development.
Catalogue number: AP0292P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q04759
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-PKC 0 (T538). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Protein kinase C theta type; nPKC-theta; PRKCQ; PRKCT
Additional info: This peptide can be used with studies using AP0292 p-PKC 0 (T538) pAb.

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