p-PKC alpha (T638) Peptide

Cat no: AP0290P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma ) and novel (n) PKC isoforms (delta, E, ?, ? and 0). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and E are independent of Ca2+.

Catalogue number:	AP0290P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P17252
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-PKC alpha (T638). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Protein kinase C alpha type; PKC-A; PKC-alpha; PRKCA; PKCA; PRKACA
Additional info:	This peptide can be used with studies using AP0290 p-PKC alpha (T638) pAb.

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p-PKC alpha (T638) Peptide

Cat no: AP0290P

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