p-PPARgamma (S112) Peptide

Cat no: BS4444P

Supplier: Bioworld Technology, Inc.

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PPAR gamma is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR gamma activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPAR gamma may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPAR gamma2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPAR gamma2 gene maybe correlated with abdominal obesity in type 2 diabetes.

Catalogue number:	BS4444P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P37231
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide p-PPARgamma (S112). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Peroxisome proliferator-activated receptor gamma; Short name=PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG; NR1C3; PPAR gamma ; PPARgamma
Additional info:	This peptide can be used with studies using BS4444 p-PPARgamma (S112) pAb.

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p-PPARgamma (S112) Peptide

Cat no: BS4444P

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