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p-SHP-2 (Y542) Peptide

p-SHP-2 (Y542) Peptide

Cat no: BS4170P


Supplier: Bioworld Technology, Inc.
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Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog.
Catalogue number: BS4170P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q06124
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-SHP-2 (Y542). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: PTPN11; BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; SHPTP2
Additional info: This peptide can be used with studies using BS4170 p-SHP-2 (Y542) pAb.

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