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p-SHP-2 (Y542) Peptide

Cat no: BS4170P

p-SHP-2 (Y542) Peptide

Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog.

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SPECIFICATIONS

Catalog Number

BS4170P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide p-SHP-2 (Y542). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q06124

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS4170 p-SHP-2 (Y542) pAb.

Alternative Names

PTPN11; BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; SHPTP2

SUPPLIER INFO

Bioworld Technology, Inc.

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