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p-SHP-2 (Y580) Peptide

p-SHP-2 (Y580) Peptide

Cat no: BS4171P

Supplier: Bioworld Technology, Inc.
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Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog.
Catalogue number: BS4171P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q06124
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-SHP-2 (Y580). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: PTP 1D , PTP 2C , PTP-1D , PTP-2C , PTP1D , PTP2C , PTPN 11 , PTPN11 , PTPN11 , SAP2 , SH PTP2 , SH PTP3 , SH-PTP2 , SH-PTP3 , SH2 domain containing protein tyrosine phosphatase 2 , SHIP2 , SHP 2 , SHP-2 , Shp2 , SHPTP 2 , SHPTP2 , SHPTP3 ,
Additional info: This peptide can be used with studies using BS4171 p-SHP-2 (Y580) pAb.

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