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p-STAM2 (Y192) pAb

p-STAM2 (Y192) pAb

Cat no: BS4876


Supplier: Bioworld Technology, Inc.
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STAM contains an SH3 (Src homology 3) motif as well as an immunoreceptor tyrosine-based activation (ITAM) motif, both of which appear to be required for c-Myc induction in response to IL-2 and GM-CSF. STAM associates with JAK3 and JAK2 via its ITAM region, and it is tyrosine phosphorylated by JAK3 and JAK2 after stimulation with IL-2 and GM-CSF, respectively. STAM2, also known as Hbp, is a protein that is highly related to STAM. Similar to STAM, STAM2 functions downstream of JAK kinases and can be phosphorylated in response to cytokines. Due to alternative splicing events, two isoforms of STAM2 exist, namely STAM2A and STAM2B.
Catalogue number: BS4876
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: O75886
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human STAM2 around the phosphorylation site of Tyrosine 192.
Species: p-STAM2 (Y192) pAb detects endogenous levels of STAM2 protein only when phosphorylated at Tyr192.
Molecular weight: ~ 58 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein; STAM2; HBP
Additional info: For research use only, not for use in diagnostic procedure.

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