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p-Syk (Y525) Peptide

p-Syk (Y525) Peptide

Cat no: BS4189P

Supplier: Bioworld Technology, Inc.
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Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigenesis. Two isoforms of Syk, designated short and long, exist due to alternative splicing events.
Catalogue number: BS4189P
Applications: Block/Neutralize/Inhibit
Swiss prot: P43405
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Syk (Y525). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk; SYK
Additional info: This peptide can be used with studies using BS4189 p-Syk (Y525) pAb.

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