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p-Tuberin/ Tsc2 (S1254) Peptide

p-Tuberin/ Tsc2 (S1254) Peptide

Cat no: BS5044P

Supplier: Bioworld Technology, Inc.
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Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.
Catalogue number: BS5044P
Applications: Block/Neutralize/Inhibit
Swiss prot: P49815
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Tuberin/ Tsc2 (S1254). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Tuberin; Tuberous sclerosis 2 protein; TSC2; TSC4
Additional info: This peptide can be used with studies using BS5044 p-Tuberin/ Tsc2 (S1254) pAb.

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