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p-VASP (S157) pAb

p-VASP (S157) pAb

Cat no: BS4722

Supplier: Bioworld Technology, Inc.
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VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is a protein of between 46 and 50 kDa that is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.
Catalogue number: BS4722
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P50552
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic phosphopeptide derived from human VASP around the phosphorylation site of Serine 157.
Species: p-VASP (S157) pAb detects endogenous levels of VASP protein only when phosphorylated at Ser157.
Molecular weight: ~48 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Vasodilator-stimulated phosphoprotein; VASP
Additional info: For research use only, not for use in diagnostic procedure.

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