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p-Vav1 (Y174) Peptide

p-Vav1 (Y174) Peptide

Cat no: BS4724P


Supplier: Bioworld Technology, Inc.
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The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins; deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages.
Catalogue number: BS4724P
Applications: Block/Neutralize/Inhibit
Swiss prot: P15498
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Vav1 (Y174). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Flk - 1 / KDR / VEGFR2; VEGFR-2; EC 2.7.10.1; Kinase insert domain receptor; Protein-tyrosine kinase receptor Flk-1; CD309 antigen; VEGFR2; 16542; Kdr; 6130401C07; Flk-1; Flk1; Krd-1; Ly73; VEGFR-2; VEGFR2; 3791; KDR; 191306; P35
Additional info: This peptide can be used with studies using BS4724 p-Vav1 (Y174) pAb.

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