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p-VE-Cadherin (Y731) Peptide

p-VE-Cadherin (Y731) Peptide

Cat no: BS4242 P


Supplier: Bioworld Technology, Inc.
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The cadherins are a family of Ca 2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.
Catalogue number: BS4242 P
Applications: Block/Neutralize/Inhibit
Swiss prot: P33151
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-VE-Cadherin (Y731). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144; CDH5; Cadherin 5
Additional info: This peptide can be used with studies using BS4242 p-VE-Cadherin (Y731) pAb.

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