P2RY1 (P2Y Purinoceptor 1, P2Y1, ATP Receptor, Purinergic Receptor)

Cat no: P1003-26M

Supplier: United States Biological

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Additional Information

Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	P1003-26M
Reactivities:	Human, Mouse, Rat, Canine
Hosts:	Goat
Applications:	ELISA
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Arthur JF, Shen Y, Mu FT, Leon C, Gachet C, Berndt MC, Andrews RK. Calmodulin interacts with the platelet ADP receptor P2Y1. Biochem J. 2006 Sep 15;398(3):339-43.
Additional info:	Recognizes P2RY1. Species sequence homology: Canine, human, mouse and rat.

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P2RY1 (P2Y Purinoceptor 1, P2Y1, ATP Receptor, Purinergic Receptor)

Cat no: P1003-26M

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