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PAI-3 (L291) Peptide

PAI-3 (L291) Peptide

Cat no: BS3152P


Supplier: Bioworld Technology, Inc.
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PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.
Catalogue number: BS3152P
Applications: Block/Neutralize/Inhibit
Swiss prot: P05154
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PAI-3 (L291). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: SERBP1; CGI-55; CHD3IP; DKFZP564M2423; FLJ90489; HABP4L; PAI-RBP1; PAIRBP1
Additional info: This peptide can be used with studies using BS3152 PAI-3 (L291) pAb.

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