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PC-PLD1 (K556) Peptide

Cat no: BS1686P

PC-PLD1 (K556) Peptide

Activation of phosphatidylcholine-specific phospholipase D (PC-PLD) catalyzes the hydrolysis of phosphatidylcholine (PC) to generate phosphatidic acid (PA). Insulin activates the PLD-dependent hydrolysis of PC in plasma membranes of adipocytes by a mechanism that may involve wortmannin-sensitive phosphatidylinositol 3-kinase. In addition to the transient activation by growth factors stimulation, PC-PLD is constitutively activated in some of the Src- and Ras-transformed cells. PC-PLD is one of the target enzymes of ischemia; its decrease may cause a perturbation of PC hydrolysis and/or disorders of intracellular signal transduction or choline metabolism for acetylcholine formation in the brain.

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SPECIFICATIONS

Catalog Number

BS1686P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide PC-PLD1 (K556). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q13393

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1686 PC-PLD1 (K556) pAb.

Alternative Names

Phospholipase D1; PLD 1; hPLD1; EC 3.1.4.4; Choline phosphatase 1; Phosphatidylcholine-hydrolyzing phospholipase D1; PLD1

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