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PCNA (I88) Peptide

PCNA (I88) Peptide

Cat no: BS1289P

Supplier: Bioworld Technology, Inc.
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The proliferating cell nuclear antigen (PCNA), a protein synthesized in early G1 and S phases of the cell cycle, functions in cell cycle progression, DNA replication, and DNA repair. In early S phase, PCNA exhibits granular distribution and is absent from the nucleoli, however, in late S phase, it relocates to the nucleoli. PCNA exists in two basic forms, one involved in ongoing DNA replication. which localizes specifically to the nucleus, and a second, soluble form, not implicated in constant synthesis. Interestingly, the latter form degrades in the presence of organic solvents, rendering it undetectable by histological methods in tissues using organic fixatives, and thus also providing a method of visualizing only the synthesizing form.
Catalogue number: BS1289P
Applications: Block/Neutralize/Inhibit
Swiss prot: P12004
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PCNA (I88). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Proliferating cell nuclear antigen; Cyclin
Additional info: This peptide can be used with studies using BS1289 PCNA (I88) pAb.

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