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PD-123319 Bis(trifluoroacetate) Salt Hydrate

PD-123319 Bis(trifluoroacetate) Salt Hydrate

Cat no: 019154

Supplier: United States Biological
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A selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has protective effect against tumor necrosis factor-a-induced damage to human renal proximal tubular epithelial cells Form: Pale Beige Solid Melting Point: 111-114 degrees C Solubility: Chloroform, Methanol Pfizer Compound
Catalogue number: 019154
Size: 10mg
Form: Pale Beige Solid
Alternative names: (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319 Bis(trifluoroacetate) Salt Hydrate;
References: Carmeiros-Ramos, M.S. et al.: Bas. Res, Cardiol., 105, 325 (2010); Kagawa, T. et al.: Nephrol., 13, 309 (2008); Cohen, E.P. et al.: Transl. Res., 150, 106 (2007);

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