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PDCD1 Peptide

PDCD1 Peptide

Cat no: BS60383P

Supplier: Bioworld Technology, Inc.
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PDCD1 (Programmed Cell Death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. Pdcd-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) within the cytoplasmic domain, which is conserved between the mouse and human homologs. Expression of Pdcd-1 is detected in mouse thymus, and it is induced in stimulated B and T cell lines, where it may play a role in the negative regulation of various immune responses. Receptors such as Pdcd-1 function by recruiting tyrosine phosphatases, including SHP-1 and SHIP, which are responsible for altering various B cell responses. Additionally, in activated lymphocytes, Pdcd-1 mediates the activation of the classical type of programmed cell death.
Catalogue number: BS60383P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q15116
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PDCD1. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Programmed cell death protein 1; Protein PD-1; hPD-1; CD279; PD1
Additional info: This peptide can be used with studies using BS60383 PDCD1 pAb.

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