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PDE1A (Calcium/Calmodulin-dependent 3',5'-cyclic Nucleotide Phosphodiesterase 1A, Cam-PDE 1A, 61kD Cam-PDE, hCam-1)

PDE1A (Calcium/Calmodulin-dependent 3',5'-cyclic Nucleotide Phosphodiesterase 1A, Cam-PDE 1A, 61kD Cam-PDE, hCam-1)

Cat no: P4072A1

Supplier: United States Biological
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Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 1-3ug/ml, human brain (cerebellum) lysates observed on ~55kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P4072A1
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Cabanero M, Laje G, Detera-Wadleigh S, McMahon FJ, Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample. Pharmacogenetics and genomics 2009 Mar 19(3):235-8.
Additional info: Recognizes human PDE1A. Species sequence homology: Bovine, mouse and rat.

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