Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-AA is a 28.5kD A chain homodimer protein containing 250aa residues.
Source:
Recombinant corresponding to human PDGF-AA expressed in E.coli.
Molecular weight:
~29kD
Biological Activity:
The activity is calculated by the dose-dependent proliferation of mouse 3T3 indicator cells and is typically 3