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PDGF-B (L48) Peptide

PDGF-B (L48) Peptide

Cat no: BS1290P

Supplier: Bioworld Technology, Inc.
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PDGF is a mitogen for mesenchyme- and glia-derived cells. It consists of two disulfide-bonded polypeptide chains, A and B, and occurs as three isoforms, PDGF AA, PDGF AB and PDGF BB. The three isoforms bind with different affinities to two receptor types, alpha and beta, which are structurally related and endowed with protein-tyrosine kinase domains. Ligand binding induces activation of the receptor kinases by formation of receptor dimers; the A subunit of PDGF binds only to alpha receptors with high affinity, whereas the B subunit can bind to both alpha and beta receptors. Evidence suggests that PDGF may function as a neurotrophic factor.
Catalogue number: BS1290P
Applications: Block/Neutralize/Inhibit
Swiss prot: P01127
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PDGF-B (L48). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Platelet-derived growth factor subunit B; PDGF subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Proto-oncogene c-Sis; Becaplermin; PDGFB; PDGF2; SIS
Additional info: This peptide can be used with studies using BS1290 PDGF-B (L48) pAb.

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