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PDGFR-(alpha) (S1057) pAb

PDGFR-(alpha) (S1057) pAb

Cat no: BS1684

Supplier: Bioworld Technology, Inc.
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Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.
Catalogue number: BS1684
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P16234
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 1020-1070 of Human PDGFR-(alpha).
Species: PDGFR-(alpha) (S1057) pAb detects endogenous levels of PDGFR-(alpha) protein.
Molecular weight: ~ 140, 190 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: PDGF Receptor alpha ( phospho Y742 ); EC 2.7.10.1; PDGF-R-alpha; CD140 antigen-like family member A; CD140a antigen; CD140a antigen; PDGFR alpha
Additional info: For research use only, not for use in diagnostic procedure.

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