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PDGFR-alpha (S1057) Peptide

Cat no: BS1684P

PDGFR-alpha (S1057) Peptide

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

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SPECIFICATIONS

Catalog Number

BS1684P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide PDGFR-alpha (S1057). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P16234

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1684 PDGFR-alpha (S1057) pAb.

Alternative Names

PDGF Receptor alpha ( phospho Y742 ); EC 2.7.10.1; PDGF-R-alpha; CD140 antigen-like family member A; CD140a antigen; CD140a antigen; PDGFR alpha

SUPPLIER INFO

Bioworld Technology, Inc.

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