PEA-15 (D110) Peptide

Cat no: BS1573P

Supplier: Bioworld Technology, Inc.

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PEA-15 (phosphoprotein enriched in astrocytes) exists in an non-phosphorylated form (N), and two phosphorylated forms, Pa and Pb. PEA-15 is an endogenous substrate for PKC, which mediates the transition from Pa to Pb. The level of PEA-15 phosphorylation changes upon depolymerization or stabilization of tubulins, indicating that PEA-15 co-localizes with microtubules. The first 80 amino acids of PEA-15 correspond to the death effector domain (DED), which is a domain found in proteins that regulate apoptotic signaling pathways. The DED domain is necessary for PEA-15 to block Ras suppression. Although PEA-15 is predominantly expressed in the central nervous system, low levels of PEA-15 are expressed in liver and kidney, and higher levels in muscle.PEA-15 is also referred to as PED, phosphoprotein enriched in diabetes, for its elevated expression in type 2 diabetic patients

Catalogue number:	BS1573P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q15121
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide PEA-15 (D110). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	PEA15 (phospho S116); Phosphoprotein enriched in diabetes; PED; PEA15; HMAT1; HUMMAT1H; MAT1; MAT1H; PEA 15; PED
Additional info:	This peptide can be used with studies using BS1573 PEA-15 (D110) pAb.

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PEA-15 (D110) Peptide

Cat no: BS1573P

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