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Per3 (P2) Peptide

Per3 (P2) Peptide

Cat no: BS2288P


Supplier: Bioworld Technology, Inc.
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Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. A number of transcription factors appearing to be molecular components of the SCN clock have been identified. Mutations within the Clock gene increase the length of the endogenous period and cause a loss of rhythmicity of circadian oscillations. Three mammalian period proteins, designated Per1, Per2 and Per3, exhibit circadian rhythyms in the SCN.During subjective night, Per1 and Per2 RNA levels increase in response to light pulses while Per3 RNA levels show no change in response to light pulses. Tim, for timeless, interacts with Per1 as well as Per2; and Tim and Per1 negatively regulate Clock-BMAL1-induced transcription.
Catalogue number: BS2288P
Applications: Block/Neutralize/Inhibit
Swiss prot: P56645/Q8TAR6
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Per3 (P2). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: PER3; GIG13; HPER3
Additional info: This peptide can be used with studies using BS2288 Per3 (P2) pAb.

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